Can Gatterman-Koch reaction be considered similar to Friedel-Craft's acylation? Discuss.
In Gatterman-Koch reaction, benzene or its derivative is treated with CO and HCl in presence of anhydrous aluminium chloride to produce benzaldehyde.
This can be done by reaction of benzene with acyl chloride in the presence of anhydrous $\mathrm{AlCl}_3$.
Formerly chloride is unstable in nature. So, it can be transferred by only Gattermann-Koch reaction not by Friedel-Craft reaction.
Match the common names given in Column I with the IUPAC names given in Column II.
| Column I (Common names) |
Column II (IUPAC names) |
||
|---|---|---|---|
| A. | Cinnamaldehyde | 1. | Pentanal |
| B. | Acetophenone | 2. | Prop-2-en-al |
| C. | Valeraldehyde | 3. | 4-methylpent-3-en-2-one |
| D. | Acrolein | 4. | 3-phenylprop-2-en-al |
| E. | Mesityl oxide | 5. | 1-phenylethanone |
A. $\rightarrow(4)$ B. $\rightarrow$ (5) C. $\rightarrow$ (1) D. $\rightarrow$ (2) E. $\rightarrow(3)$
| Common names | Structure | IUPAC names | |
|---|---|---|---|
| A. | Cinnamaldehyde |  |
3-phenylprop-2-en-al |
| B. | Acetophenone |  |
1-phenylethanone |
| C. | Valeraldehyde |  |
Pentanal |
| D. | Acrolein |  |
Prop-2-en-al |
| E. | Mesityl oxide |  |
4-methyl pent-3-en-2-one |
Match the acids given in Column I with their correct IUPAC names given in Column II.
| Column I (Acids) |
Column II (IUPAC names) |
||
|---|---|---|---|
| A. | Phthalic acid | 1. | Hexane-1, 6-dioic acid |
| B. | Oxalic acid | 2. | Benzene-1, 2-dicarboxylic acid |
| C. | Succinic acid | 3. | Pentane-1, 5-dioic acid |
| D. | Adipic acid | 4. | Butane-1, 4-dioic acid |
| E. | Glutaric acid | 5. | Ethane-1, 2-dioic acid |
$\begin{array}{llll}\text { A. } \rightarrow(2) & \text { B. } \rightarrow(5) & \text { C. } \rightarrow(4) & \text { D. } \rightarrow(1) \\ \text { E. } \rightarrow(3)\end{array}$
| Acids | IUPAC names | Structure | |
|---|---|---|---|
| A. | Phthalic acid | Benzene-1, 2-dicarboxylic acid |  |
| B. | Oxalic acid | Ethane-1, 2-dioic acid |  |
| C. | Succinic acid | Butane-1, 4-dioic acid |  |
| D. | Adipic acid | Hexane-1, 6-dioic acid |  |
| E. | Glutaric acid | Pentane-1, 5-dioic acid |  |
Match the reactions given in Column I with the suitable reagents given in Column II.
| Column I (Reactions) |
Column II (Reagents) |
||
|---|---|---|---|
| A. | Benzophenone $\to$ Diphenylmethane | 1. | LiAlH$_4$ |
| B. | Benzaldehyde $\to$ 1-phenylethanol | 2. | DIBAL-H |
| C. | Cyclohexanone $\to$ Cyclohexanol | 3. | Zn(Hg)/Conc. HCl |
| D. | Phenyl benzoate $\to$ Benzaldehyde | 4. | CH$_3$MgBr |
A. $\rightarrow(3)$ B. $\rightarrow$ (4) C. $\rightarrow$ (1) D. $\rightarrow(2)$
| Reactions | Reagents | ||
|---|---|---|---|
| A. |  |
1. | Zn(Hg)/Conc. HCl |
| B. |  |
2. | CH$_3$MgBr |
| C. |  |
3. | LiAlH$_4$ |
| D. |  |
4. | DIBAL-H |
Match the example given in Column I with the name of the reaction in Column II.
| Column I (Example) |
Column II (Reaction) |
||
|---|---|---|---|
| A. |  |
1. | Friedel-Crafts acylation |
| B. |  |
2. | HVZ reaction |
| C. |  |
3. | Aldol condensation |
| D. |  |
4. | Cannizzaro's reaction |
| E. | $\mathrm{CH}_3-\mathrm{CN} \xrightarrow[\text { (ii) } \mathrm{H}_2 \mathrm{O} / \mathrm{H}^{+}]{\text {(i) } \mathrm{SnCl}_2 / \mathrm{HCl}} \mathrm{CH}_3 \mathrm{CHO}$ | 5. | Rosenmund's reduction |
| F. | $2 \mathrm{CH}_3 \mathrm{CHO} \xrightarrow{\mathrm{NaOH}} \mathrm{CH}_3-\mathrm{CH}=\mathrm{CHCHO}$ | 6. | Stephen's reaction |
A. $\rightarrow$ (5) B. $\rightarrow(4)$ C. $\rightarrow(1)$ D. $\rightarrow$ (2) E. $\rightarrow$ (6) F. $\rightarrow(3)$
Example |
Name of the Reaction |
||
|---|---|---|---|
| A. | |
1. | Rosenmund's reduction |
| B. | |
2. | Cannizzaro's reaction |
| C. | |
3. | Friedel-Crafts acylation |
| D. | |
4. | HVZ reaction |
| E. | $\mathrm{CH}_3-\mathrm{CN} \xrightarrow[\text { (ii) } \mathrm{H}_2 \mathrm{O} / \mathrm{H}^{+}]{\text {(i) } \mathrm{SnCl}_2 / \mathrm{HCl}} \mathrm{CH}_3 \mathrm{CHO}$ | 5. | Stephen's reduction |
| F. | $2 \mathrm{CH}_3 \mathrm{CHO} \xrightarrow{\mathrm{NaOH}} \mathrm{CH}_3-\mathrm{CH}=\mathrm{CHCHO}$ | 6. | Aldol condensation |