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21

Respiration is an energy releasing and enzymatically controlled catabolic process which involves a step-wise oxidative breakdown of organic substances inside living cells. In this statement about respiration explain the meaning of

(a) Step-wise oxidative breakdown

(b) Organic substances (used as substrates).

Explanation

(a) Respiration is a stepwise oxidation of organic molecules in a cell involving main three steps.

(i) Glycolysis (ii) Krebs' cycle (iii) Electron transport chain

Glucose passes through series of enzymatically controlled reactions and is finally converted into $\mathrm{H}_2 \mathrm{O}+$ ATP $+\mathrm{CO}_2$.

(b) Organic substances are the molecules normally found in living systems. They are usually composed of carbon atoms in rings or long chains to which other atoms such as hydrogen, oxygen and nitrogen are attached. e.g., glucose, fatty acids, amino acids etc. These molecules burnt as substrate to produce energy. Respiration of glucose and fatty acids is called floating respiration and respiration of protein and amino acids are called protoplasmic respiration.

22
Comment on the statement respiration is an energy producing process but ATP is being used in some steps of the process.
Explanation
Respiration is necessary catabolic process which occurs in stepwise to produce energy. Whenever biological system requires energy it is provided by hydrolysis of ATP molecule. When one ATP is hydrolysed to ADP + Pi, i.e., one phosphate bond is broken down, thus producing 73 kcal energy. Thus, ATP is utilised only when it is required so as to maintain the respiratory balance sheet.
23

The figure given below shows the steps in glycolysis. Fill in the missing steps $A, B, C, D$ and also indicate whether ATP is being used up or released at step $E$ ?

Explanation

Process of glycolysis is summarised as follow

24
Why is respiratory pathway referred to as an amphibolic pathway?
Explanation

Glucose is the favourite sulphate for respiration as carbohydrates are first converted into glucose. Prior to used for respiration. Fats are acetyl CO-A are broken down into glycerol and fatty acid which is further degraded into acetyl Co-A, while protein is degraded into, smaller units anino acids. Respiratory process involves the breaking down of substrate is catabolic proceses. Sometime the fatty acid is required them synthesis of it occurs by withdrawing acetly Co-A. This synthesising phase is the anabolic process.

Thus, respiratory pathway involves the catabolic process (break down) and anabolic pathway synthesis of molecules using respiratory intermediates frant link, it is called as an amphibolic pathway.

25
We commonly call ATP as the energy currency of the cell. Can you think of some other energy carriers present in a cell? Name any two.
Explanation
An energy carrier is a highly specialised molecule that transfers, recieves and stores energy within the cell. This energy is then used to facilitate the chemical reactions within the cell. The three major types of energy carriers are ATP, NADPH and NADH.