Match the classes of drugs given in Column I with their action given in Column II.
| Column I | Column II | ||
|---|---|---|---|
| A. | Analgesics | 1. | Inhibit the growth of microorganisms can be given orally |
| B. | Antiseptics | 2. | Treatment of stress |
| C. | Antihistamines | 3. | Applied to inanimate objects |
| D. | Antacids | 4. | Prevents the interaction of histamine with its receptor |
| E. | Tranquilizers | 5. | Pain killing effect |
| F. | Antibiotics | 6. | Applied to diseased skin surfaces |
| G. | Disinfectants | 7. | Treatment of acidity |
A. $\rightarrow$ (5) B. $\rightarrow(6)$ C. $\rightarrow(4)$ D. $\rightarrow$ (7) E. $\rightarrow$ (2) F. $\rightarrow$ (1) G. $\rightarrow(3)$
A. Analgesics reduce or abolish pain without causing impairment of consciousness, mental confusion, in coordination or paralysis or some other disturbances of nervous system, e.g., aspirin.
B. Antiseptics are the chemicals which either kill or prevent the growth of mircoorganisms. They are applied to living tissues such as wounds, cuts etc., e.g., tincture of iodine.
C. Antihistamines are anti-allergic drugs. These drugs interfere with the natural action of histamine by competing with histamine for binding sites of receptor where histamine exerts its effect. e.g., seldane.
D. Antacids are used to neutralise excess of acid released in stomach e.g., mixture of $\mathrm{Mg}(\mathrm{OH})_2$ and $\mathrm{Al}(\mathrm{OH})_3$.
E. Tranquilizers are used for the treatment of stress, and mild or even severe mental diseases e.g., equanil.
F. Antibiotics are antimicrobial drugs. Antibiotics are used as drugs to treat infections because of their low toxicity for humans and animals e.g., chloramphenicol.
G. Disinfectants are the chemicals which either kill or prevent the growth of microorganisms but they can be applied on non-living objects e.g., 1 per cent solution of phenol.
Assertion (A) Penicillin (G) is an antihistamine.
Reason (R) Penicillin (G) is effective against gram positive as well as gram negative bacteria.
Assertion (A) Sulpha drug contain sulphonamide group.
Reason (R) Salvarsan is a sulpha drug.
Assertion (A) Receptors are crucial to body's communication process.
Reason (R) Receptors are proteins.
Assertion (A) Enzymes have active sites that hold substrate molecule for a chemical reaction.
Reason (R) Drugs compete with natural substrate by attaching covalently to the active site of enzyme.