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38
Subjective

Name the enzymes and write the reactions involved in the preparation of ethanol from sucrose by fermentation.

Explanation

Sucrose is converted to glucose and fructose in the presence of an enzyme, invertase or sucrase. Glucose and fructose undergo fermentation in the presence of another enzyme, zymase. Both these enzymes are present in yeast.

$\underset{\text { Sucrose }}{\mathrm{C}_{12} \mathrm{H}_{22} \mathrm{O}_{11}}+\mathrm{H}_2 \mathrm{O} \xrightarrow{\text { Invertase/sucrose }} \underset{\text { Glucose }}{\mathrm{C}_6 \mathrm{H}_{12} \mathrm{O}_6}+\underset{\text { Fructose }}{\mathrm{C}_6 \mathrm{H}_{12} \mathrm{O}_6}$

$\underset{\substack{\text { Glucose /Fructose }}}{\mathrm{C}_6 \mathrm{H}_{12} \mathrm{O}_6} \xrightarrow{\text { Zymase }} \underset{\substack{\text { Ethanol }}}{2 \mathrm{CH}_3 \mathrm{CH}_2 \mathrm{OH}}+2 \mathrm{CO}_2$

39
Subjective

How can propan-2-one be converted into tert-butyl alcohol?

Explanation

Propan-2-one is a ketone. Its structural formula is ketones when treated with Grignard reagent give tertiary alcohols.

40
Subjective

Write the structures of the isomers of alcohols with molecular formula $\mathrm{C}_4 \mathrm{H}_{10} \mathrm{O}$. Which of these exhibits optical activity?

Explanation

Some compounds can rotate the plane polarised light, when it is passed through their solution. Such compounds are called optically active compounds. The structures of the isomers of alcohols with molecular formula $\mathrm{C}_4 \mathrm{H}_{10} \mathrm{O}$ are as follows

(i) $\mathrm{CH}_3-\mathrm{CH}_2-\mathrm{CH}_2-\mathrm{CH}_2-\mathrm{OH}$ Butan-1-ol
(ii) Butan-2-ol
(iii) 2-methylpropan-1-ol
(iv) 2-methylpropan-2-ol

The asymmetry of the molecule is responsible for the optical activity in a molecule. If all the four substituents attached to the carbon are different then the carbon is called asymmetric or chiral carbon and such a molecule is called asymmetric molecule. In the above explained structure, it is only butan-2-ol which contains a chiral carbon and hence it is optically active.

41
Subjective

Explain why is OH group in phenols more strongly held as compared to OH group in alcohols?

Explanation

In phenols, the electron pairs on oxygen atom of -OH group are in conjugation (or resonance) with $\pi$ electrons of the ring and the following resonating structures are possible

Out of these five resonating structures, II, III and IV structures contain a carbon-oxygen double bond character. In other words, carbon-oxygen bond in phenol acquires a partial double bond character due to resonance. But in alcohols carbon-oxygen bond in alcohols is purely single bond. Therefore, -OH group in phenols is more strongly held as compared to - OH group in alcohols.

42
Subjective

Explain why nucleophilic substitution reactions are not very common in phenols?

Explanation

Resonance is an important factor in phenols. During resonance -OH group in phenol gives its electrons to the benzene ring. As a result of this, the electron density on benzene ring is very high. This increased electron density repels nucleophiles.

Therefore, nucleophiles cannot attack the benzene ring and phenols usually do not give nucleophilic substitution reaction.